Cancer
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Multicenter Study
The role of tumor resection in the treatment of glioblastoma multiforme in adults.
The therapeutic impact of tumor resection is poorly defined. Therefore the current study was conducted. ⋯ For RTOG Classes IV-VI patients with moderate mass effect of the tumor, radiation therapy alone is a rational treatment strategy. Tumor resection should be performed in patients with pretreatment midline shift whenever possible.
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Randomized Controlled Trial Multicenter Study Clinical Trial
A randomized comparison of indwelling pleural catheter and doxycycline pleurodesis in the management of malignant pleural effusions.
The purpose of this study was to compare the effectiveness and safety of a chronic indwelling pleural catheter with doxycycline pleurodesis via tube thoracostomy in the treatment of patients with recurrent symptomatic malignant pleural effusions (MPE). ⋯ A chronic indwelling pleural catheter is an effective treatment for the management of patients with symptomatic, recurrent, malignant pleural effusions. When compared with doxycycline pleurodesis via tube thoracostomy, the pleural catheter requires a shorter hospitalization and can be placed and managed on an outpatient basis.