Gastroenterology
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Randomized Controlled Trial Multicenter Study
Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease.
There are no effective and safe treatments for chronic hepatitis C virus (HCV) infection of patients who have advanced liver disease. ⋯ The combination of ledipasvir, sofosbuvir, and ribavirin for 12 weeks produced high rates of SVR12 in patients with advanced liver disease, including those with decompensated cirrhosis before and after liver transplantation. ClinTrials.gov: NCT01938430.