Eur J Gynaecol Oncol
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Eur J Gynaecol Oncol · Jan 2011
Randomized Controlled TrialEfficiency of postoperative pain management after gynecologic oncological surgeries with the use of morphine + acetaminophen + ketoprofen versus morphine + metamizol + ketoprofen.
Surgical treatment used in gynecological oncology involves acute postoperative pain which requires efficient treatment. This study covered a group of 128 patients who were randomly divided into two groups. In the postoperative period patients in group I were administered morphine subcutaneously, acetaminophen intravenously and naproxen per rectum. ⋯ In group I after the administration of morphine and acetaminophen 22 patients (34.37%) needed additional doses of ketoprofen. In group II 33 women (51.56%) required ketoprofen after the administration of morphine and metamizole (N1 = 22 vs N2 = 33, p < 0.05). The use of metamizol with morphine (without ketoprofen) gave worse analgesic results than acetaminophen with morphine, but the combination of morphine, acetaminophen and ketoprofen or morphine, metamizol and ketoprofen gave satisfactory analgesic results.
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Eur J Gynaecol Oncol · Jan 2009
Randomized Controlled TrialThe role of immunonutrition in gynecologic oncologic surgery.
This study assesses the effect of immunonutrition on biochemical and hematological parameters, incidence of infection, postoperative complications, mortality rate and length of hospital stay. ⋯ Perioperative immunonutrition proved to be safe and useful in increasing the immunologic response. It may decrease postoperative complications and LOS in patients undergoing surgery for gynecological malignancy.
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Eur J Gynaecol Oncol · Jan 2006
Randomized Controlled Trial Comparative StudyComparison of lornoxicam with tramadol in patient-controlled analgesia after gynecological surgery.
The aim of this study was to compare the effects of lornoxicam and tramadol in patient-controlled analgesia (PCA) after gynecological surgery. ⋯ Tramadol and lornoxicam may be used for pain control after gynecological surgery via PCA. However, we conclude that tramadol has better analgesic efficacy than lornoxicam during the first 12 hours postoperatively.
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Eur J Gynaecol Oncol · Jan 2004
Randomized Controlled Trial Clinical TrialPostoperative patient-controlled analgesia with intravenous tramadol, intravenous fentanyl, epidural tramadol and epidural ropivacaine+fentanyl combination.
The aim of this study was to compare the effects of IV tramadol, IV fentanyl, epidural tramadol, and an epidural ropivacaine+fentanyl combination in patient-controlled analgesia (PCA) after lower abdominal surgery. ⋯ Although adequate pain relief was achieved with all regimens that were used in the study, intravenous tramadol and intravenous fentanyl are associated with a high incidence of nausea and vomiting.
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Eur J Gynaecol Oncol · Jan 2004
Randomized Controlled Trial Clinical TrialThe efficacy of intravenous versus epidural tramadol with patient-controlled analgesia (PCA) in gynecologic cancer pain.
We attempted to compare the analgesic effects of tramadol infusion intravenously and epidurally administered through a patient-controlled analgesia (PCA) method for postoperative analgesia following gynaecological cancer surgery. Forty patients undergoing elective cancer surgery, included in the American Society of Anesthesiologists (ASA) class II and III, were randomly placed into two groups. The patients in the intravenous (IVA) group were administered a 20 mg bolus of tramadol intravenously and the patients in the epideral analgesia (EA) group epidurally five minutes before induction. ⋯ VAS values of patients, 6.85 +/- 1.34 and 3.00 +/- 1.58, respectively, for the IVA group (group 1) and the EA group (group 2) were found to be significantly different. Postoperative patient satisfaction was higher was in group 2 than in group 1 (3.45 and 2.7, respectively). In conclusion, epidural administration of tramadol through the PCA method following gynecologic cancer surgery was found to be a more effective analgesia in lower doses when compared to the intravenous administration.