J Bone Joint Surg Br
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J Bone Joint Surg Br · Jul 2009
Review Meta Analysis Comparative StudyA comparison of regional and general anaesthesia for total replacement of the hip or knee: a meta-analysis.
We performed a meta-analysis to evaluate the relative efficacy of regional and general anaesthesia in patients undergoing total hip or knee replacement. A comprehensive search for relevant studies was performed in PubMed (1966 to April 2008), EMBASE (1969 to April 2008) and the Cochrane Library. Only randomised studies comparing regional and general anaesthesia for total hip or knee replacement were included. ⋯ A random-effects model was used to calculate all effect sizes. Pooled results from these trials showed that regional anaesthesia reduces the operating time (odds ratio (OR) -0.19; 95% confidence interval (CI) -0.33 to -0.05), the need for transfusion (OR 0.45; 95% CI 0.22 to 0.94) and the incidence of thromboembolic disease (deep-vein thrombosis OR 0.45, 95% CI 0.24 to 0.84; pulmonary embolism OR 0.46, 95% CI 0.29 to 0.80). Regional anaesthesia therefore seems to improve the outcome of patients undergoing total hip or knee replacement.
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This review discusses the causes, outcome and prevention of whiplash injury, which costs the economy of the United Kingdom approximately pound 3.64 billion per annum. Most cases occur as the result of rear-end vehicle collisions at speeds of less than 14 mph. ⋯ Over 66% make a full recovery and 2% are permanently disabled. The outcome can be predicted in 70% after three months.