J Cardiovasc Surg
-
Randomized Controlled Trial Clinical Trial
Tranexamic acid reduces bleeding after off-pump coronary artery bypass grafting.
To assess the ability of tranexamic acid, compared with an untreated control group, to decrease bleeding and transfusion requirements in patients undergoing coronary artery bypass grafting on the beating heart. ⋯ Tranexamic acid reduces postoperative blood loss after coronary artery bypass grafting on the beating heart. Evaluation of transfusion requirements warrants further study.
-
Randomized Controlled Trial Clinical Trial
Does leukodepletion during elective cardiac surgery really influence the overall clinical outcome?
We examined the impact of leukocyte filtration during the entire bypass time on postoperative leukocytosis, perioperative hemorrhage and overall clinical outcome in patients undergoing elective cardiac surgery. ⋯ Leukocyte depletion contributes to early postoperative improvement in heart and lung function but does not influence significantly the overall clinical outcome of patients undergoing elective cardiac surgery.