Minerva anestesiologica
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Minerva anestesiologica · Apr 1992
Comparative Study[Tracheal intubation: increase of arterial pressure and cerebral blood flow velocity. Effect of thiopentone and propofol].
Induction of anaesthesia in intracranial surgery, especially for vascular diseases, must minimize haemodynamic changes: blood pressure and cerebral blood flow must not be increased to a high degree. Our work compares increases in blood pressure and in the speed of cerebral blood flow during endotracheal intubation in two groups of patients, who received propofol or thiopentone for the induction of anaesthesia. ⋯ Increase in blood pressure after intubation was lower with propofol than with thiopentone in a statistically significant way. Also the increase in the speed of cerebral blood flow, measured with doppler technique, was lower when induction with propofol was used, though not statistically relevant.
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One hundred and thirty three patients of both sexes were operated on for pituitary tumors with transphenoidal microsurgery. Postoperative complications are discussed.
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We present one case of pulmonary edema following intravenous naloxone administration for antagonism of residual narcotic drugs. The patient was a young man without cardiopulmonary or neurologic disease. Pathogenesis results from a massive sympathetic discharge which leads to neurogenic pulmonary edema.