Minerva anestesiologica
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Minerva anestesiologica · Oct 2000
Randomized Controlled Trial Clinical TrialClinical comparison of either small doses of fentanyl or remifentanil for blunting cardiovascular changes induced by tracheal intubation.
To compare in a prospective, randomized study the effects on cardiovascular changes after tracheal intubation produced by small doses of either remifentanil or fentanyl. ⋯ We conclude that in healthy normotensive patients, the control of cardiovascular responses to tracheal intubation obtained with a 1 microgram.kg-1 loading dose of remifentanil is more effective than that provided by a 3 micrograms.kg-1 bolus of fentanyl, with the advantage of no risks for postoperative respiratory depression.