Minerva anestesiologica
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Minerva anestesiologica · Apr 2007
Randomized Controlled TrialFluid challenge in patients submitted to spinal block.
The practice of routinely prehydrating patients by infusing a colloid solution for prevention of spinal anesthesia-induced hypotension has been challenged recently. The aim of the study was to evaluate the influence of a 15 mL/kg pre-emptive bolus of colloids (6% hydroxyhethyl starch) on heart rate (HR), mean arterial blood pressure (MAP), cardiac index (CI) in patients submitted to subarachnoid block with hyperbaric bupivacaine 0.5%, 0.2 mg/kg for orthopedic surgery of the lower limb. ⋯ Our data show that despite to fluid challenge, we could not prevent MAP decrease in Group A, even if it is more marked in Group B.
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Minerva anestesiologica · Apr 2007
Randomized Controlled Trial Comparative StudyPrevention of pain on injection of propofol: a comparison of remifentanil with alfentanil in children.
Propofol has a high incidence of pain on injection, particularly when a vein on the back of hand is used. Administration of lidocaine, either before or mixed with propofol remains the most widely used method to attenuate this pain. The use of opioids such as alfentanil and fentanyl has been found to decrease pain induced by propofol injection. The purpose of this study was to evaluate the effects of different doses of remifentanil and alfentanil in minimizing the pain caused by propofol. ⋯ Pretreatment with intravenous remifentanil 0.5 microg kg(-1), alfentanil 15 microg kg(-1) and 20 microg kg(-1) were equally effective in reducing pain associated with propofol injection in children between the age group of 5-12 years.