Minerva anestesiologica
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Minerva anestesiologica · Jul 2009
Randomized Controlled TrialSubarachnoid anesthesia vs monitored anesthesia care for outpatient unilateral inguinal herniorrhaphy.
Inguinal herniorrhaphy is one of the most commonly performed surgical procedures in a same-day surgery setting. The prerequisite of having to discharge the surgical outpatient on the same day has an influence on the choice of the anesthetic technique. ⋯ LA+TCI was shown to be more effective than selective SA at low doses in terms of shorter time to recovery after unilateral inguinal herniorrhaphy procedures.
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Minerva anestesiologica · Jul 2009
Randomized Controlled TrialEffects of recombinant human activated protein C on the fibrinolytic system of patients undergoing conventional or tight glycemic control.
Recombinant human activated protein C (rh-APC) and tight glycemic control (TGC) have been shown to reduce mortality in septic patients. Both interventions can reduce the plasma concentration and/or activity of the most powerful suppressor of fibrinolysis, plasminogen activator inhibitor-1 (PAI-1). Our aim was to evaluate the effects on the fibrinolytic system after the administration of rh-APC in septic patients undergoing conventional or TGC. ⋯ Both rh-APC and TGC appear to improve fibrinolysis in septic patients. The reduction in the impairment of fibrinolysis associated with rh-APC treatment seems greater in patients undergoing conventional glycemic control than in those undergoing TGC.