Minerva anestesiologica
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Minerva anestesiologica · Jun 2016
Randomized Controlled TrialClosed-loop ventilation mode (IntelliVent-ASV) in intensive care unit: a randomized trial of ventilation delivered.
Closed-loop modes automatically adjust ventilation settings, delivering individualized ventilation over short periods of time. The objective of this randomized controlled trial was to compare safety, efficacy and workload for the health care team between IntelliVent®-ASV and conventional modes over a 48-hour period. ⋯ IntelliVent®-ASV required less manual intervention and delivered more variable PEEP and PINSP, while delivering ventilation safe and effective ventilation in terms of VT, RR, SpO2 and PETCO2.
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Minerva anestesiologica · Jun 2016
Randomized Controlled TrialBetahistine reduces postoperative nausea and vomiting and dizziness after laparoscopic gynecological surgery.
Patients undergoing laparoscopic gynecological surgery are at high risk of postoperative nausea and vomiting (PONV). We compared the antiemetic efficacy of ondansetron plus betahistine with that of ondansetron alone in this patient population. ⋯ Compared to ondansetron alone, ondansetron plus betahistine was more effective to prevent PONV and dizziness in high-risk patients undergoing laparoscopic gynecological surgery.