Minerva anestesiologica
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Minerva anestesiologica · Sep 2017
Randomized Controlled TrialOpioid-sparing effect of nefopam in combination with paracetamol after major abdominal surgery: a randomized double-blind study.
Because nefopam's morphine-sparing is debated when combined with paracetamol, this study aimed to assess pain relief by IV nefopam in combination with paracetamol after major abdominal surgery. ⋯ This prospective randomized study suggested that nefopam in combination with paracetamol has no benefit after open abdominal surgery.
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Minerva anestesiologica · Sep 2017
Randomized Controlled Trial Comparative StudyTime-to-intubation in obese patients. A randomized study comparing direct laryngoscopy and videolaryngoscopy in experienced anaesthetists.
Airway management may be difficult in obese patients. Moreover, during prolonged intubation, oxygen desaturation develops rapidly. Videolaryngoscopy improves the view of the larynx, and the Storz® C-MAC™ has been shown to be superior to other videolaryngoscopes in terms of intubation time in obese patients. However, no effort has been made to compare the Storz® C-MAC™ with direct laryngoscopy. The aim of the study was to evaluate if the use of Storz® C-MAC™ may reduce intubation time when compared to direct laryngoscopy (classic Macintosh® blade). ⋯ In obese patients the airway may be secured equally fast using direct laryngoscopy (Macintosh®) and with videolaryngoscopy using the Stortz® C-MAC™. The risk for failed intubation, however, appears to be greater with direct laryngoscopy, especially in male obese patients.
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Minerva anestesiologica · Sep 2017
Randomized Controlled TrialIntraspinal administration of morphine hydrochloride combined with low doses of bupivacaine in hemorrhoidectomy: a clinical randomised trial.
Intrathecal local anesthetics, associated or not to opioids, is commonplace in anorectal surgery, but it is unknown which is the option with the best risk-benefit ratio. The main aim was to assess whether the combination of morphine (50 mcg) with low-dose bupivacaine (3 mg) in an intradural solution has a better analgesic short-term effect than bupivacaine alone at standard doses (5 mg) in hemorrhoidectomy. ⋯ The addition of intradural morphine allows a reduction in the dosage of local anesthetic improves short-term postoperative analgesia and is associated with less motor blockade.