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Surg J R Coll Surg E
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Surg J R Coll Surg E · Jun 2006
Randomized Controlled TrialLessons learned from a randomised controlled study of perioperative beta blockade in high risk patients undergoing emergency surgery.
Perioperative beta blockade has been shown to reduce mortality after major elective surgery. The aim of this study was to determine whether it could reduce the rate of death and morbidity from cardiac complications in high risk patients undergoing emergency surgery. ⋯ This study of emergency surgery proved more difficult than similar trials in elective surgery. The final study groups were small and there were no significant differences in outcomes. A much larger study is required for a definitive answer.