World Neurosurg
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Meta Analysis
Meta-analysis of Microarray-Based Expression Profiles to Identify Differentially Expressed Genes in Intracranial Aneurysms.
To gain comprehensive insight into the molecular mechanism of formation and rupture of intracranial aneurysms (IAs). ⋯ Inflammation, immune response, and loss of contractile vascular smooth muscle cells could potentially contribute to the formation of IAs, whereas the role of angiogenesis and vascular remodeling in IA formation and rupture needs further exploration.
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Review Case Reports
Value of targeted epidural blood patch and management of subdural hematoma in spontaneous intracranial hypotension.
Spontaneous intracranial hypotension (SIH) is a more common than previously noted condition (1-2.5 per 50,000 persons) typically caused by cerebrospinal fluid (CSF) leakage. Initial treatment involves conservative therapies, but the mainstay of treatment for patients who fail conservative management is the epidural blood patch (EBP). Subdural hematoma (SDH) is a common complication occurring with SIH, but its management remains controversial. ⋯ Although blind lumbar EBP is often successful, targeted EBP has a lower rate of patients requiring a second EBP or other further treatment. On the other hand, targeted EBP has a larger risk profile. Depending on the clinic situation, treatment of the SDH via surgical evacuation may be necessary.
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Review Case Reports
Spinal Dural Arteriovenous Fistulas with Segmental Arterial Supply Also Giving Rise to a Radiculomedullary Artery: A Case Report and Review of the Literature.
During the past 3 decades, a handful of spinal dural arteriovenous fistula cases have been reported in which the segmental artery giving rise to the fistulous connection also supplies a radiculomedullary artery that contributes to the anterior spinal artery. ⋯ Recognizing this likely rare anatomical variant is critical in optimizing functional outcome.
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The aim of this systematic review was to compare the halo and hard collar in the management of adult odontoid fractures. ⋯ For the most common clinical scenario, the halo and collar have similar failure rates, such that the higher morbidity associated with the halo may not be justified, especially in elderly patients. Malunion usually represents a stable clinical outcome, and surgery is rarely required. Prospective randomized studies are needed to more definitively compare the devices.
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Review Case Reports
Long-term Survival Primary Intracranial Plasmablastic Lymphoma: Case Report and Review of the Literature.
Primary intracranial plasmablastic lymphoma (PIPBL) is a rare malignant tumor. ⋯ This study provides important clinical information for the diagnosis and treatment of PIPBL.