World Neurosurg
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Medical professionals with both M.D. and Ph.D. degrees are increasingly expected to balance roles as clinicians and researchers, a trend particularly prevalent in China. However, little is known about how early-career Chinese neurosurgeons navigate these dual responsibilities. ⋯ This study sheds light on the complexities of professional identity construction among early-career Chinese neurosurgeons. Implications for international neurosurgeons include the need for tailored mentoring and institutional support. Limitations include the small sample size and regional focus. Future research could explore cross-cultural comparisons to further understand clinician-researcher identities.
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Review
Jacob Fidelis Ackermann (1765-1815): pioneer in the anatomical description of basilar invagination.
Jacob Fidelis Ackermann was a German Medical Doctor born in 1765 in the city of Rüdesheim. Between 1789 and 1815 years he was professor of medicine at the universities of Mainz and Heidelberg, teaching the disciplines of anatomy, physiology, botany, and natural history. ⋯ For this, he traveled through various European Alps analyzing autopsies and cranial specimens to describe the basilar invagination as an extremely inclined foramen magnum, with hypoplasia of occipital condyles, and elevation of the petrous part of the temporal bone. In his analyses, the thyroid gland dysfunction was the main etiology of the basilar invagination, in which the brainstem compression was a major pathological relevance discussed.
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A rapid and smooth emergence is essential in patients undergoing transsphenoidal pituitary surgeries. Ketofol has been used as an anesthetic agent with good recovery characteristics. We conducted this study to compare the recovery profile of the patients receiving propofol-dexmedetomidine or ketofol-dexmedetomidine infusions for transsphenoidal excision of pituitary tumors. ⋯ The use of ketofol resulted in a longer recovery time compared to the use of propofol alone. However, ketofol was associated with a better quality of extubation, maintenance of hemodynamic stability, and enhanced postoperative analgesia. Further research is needed to conclusively establish its efficacy and optimal dosage in pituitary surgery.
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To analyze the prevalence and influencing factors of stroke in patients with nonvalvular atrial fibrillation (SIPWNVAF), and to provide a reference basis for the prevention and control of stroke. ⋯ The stroke group is significantly more burdened by other independent common risk factors for stroke.
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The causal relationship between mitochondrial DNA copy number (mtDNA-CN) and intervertebral disc degeneration (IVDD) remains unclear. The study aimed to investigate the causal relationship between mtDNA-CN and IVDD using Mendelian randomization analyses. ⋯ The study revealed that there is no causal relationship of mtDNA-CN on the risk of IVDD, nor does IVDD have a significant causal effect on mtDNA-CN. Although the study did not find a significant causal relationship, it provides valuable insights into the complex interplay between genetic factors and IVDD. Further research is needed to explore to better understand the underlying mechanisms of this condition.