World Neurosurg
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Review Meta Analysis Comparative Study
Skip Laminectomy Compared with Laminoplasty for Cervical Compressive Myelopathy: A Systematic Review and Meta-Analysis.
This meta-analysis evaluated the clinical outcomes of skip laminectomy relative to laminoplasty for the treatment of cervical compressive myelopathy. ⋯ This meta-analysis determined that skip laminectomy was superior to laminoplasty in terms of visual analogue scale score and rates of axial pain and muscle atrophy. These results warrant further confirmation in future research.
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Meta Analysis Comparative Study
Biopsy Versus Subtotal Versus Gross Total Resection in Patients with Low-Grade Glioma: A Systematic Review and Meta-Analysis.
The role of the extent of surgical resection (EOR) in clinical outcomes for patients with low-grade glioma requires further examination. The goal of the present study was to evaluate the association between variable degrees of EOR and clinical outcomes for patients with low-grade glioma. ⋯ Among patients with low-grade gliomas, greater degrees of safe EOR were associated with longer OS and progression-free survival, better seizure control, and delayed malignant transformation, without increasing mortality or morbidity.
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Intracerebral hemorrhage (ICH) is the most difficult-to-treat form of stroke and accounts for about 10%-30% of all strokes worldwide. Hematoma expansion (HE), which occurs in one third of patients with ICH, is strongly predictive of worse prognosis and potentially preventable if high-risk patients are identified in the early phase of ICH. We summarized data from recent studies on HE prediction and classified those potential indicators into 2 categories: 1) clinical and laboratory and 2) radiographic. Therefore, we aimed to identify the accuracy of L, that is, the value of combining predictors in predicting HE of ICH in basal ganglia. ⋯ The findings indicated that the ability of L to predict HE was much more excellent than these 6 predictors alone. L showed a high association with HE, with an accuracy of 91.8%, and was a reliable value of combining predictors in terms of predicting HE. L may serve as a promising, noninvasive tool for clinical therapeutic strategy.
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The emergence of multidrug-resistant pathogens has resulted in difficult-to-treat ventriculitis/meningitis (VM). We used a meta-analysis to study the role of intraventricular (IVT) antibiotic administration as an adjunct (IVT plus intravenous [IV]) to the classic intravenous antimicrobial therapy (IV-only) in the management of VM in terms of infection control, functional outcome, microbial eradication, complications, cost-benefit analysis, infectious mortality, and overall mortality. ⋯ Combined IVT plus IV treatment did not prove superior to standard IV-only treatment in the management of VM. Nevertheless, weak evidence showed that IVT treatment might serve as an adjunct in the management of carbapenem-resistant pathogens.
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Multicenter Study
The Unique Features and Outcomes of Microsurgically Resected Cerebellar Arteriovenous Malformations.
Cerebellar arteriovenous malformations (CAVMs) are challenging to treat given their close proximity to the brain stem, greater propensity for rupture, and greater rates of morbidity and mortality than other brain arteriovenous malformations. The present investigation sought to describe and characterize the features of these rare and unique lesions. ⋯ CAVMs are rare lesions that exhibit unique disease characteristics. Although most patients will experience a favorable outcome, CAVMs frequently present with hemorrhage, result in high rates of morbidity and mortality, and characteristically differ depending on patient age and gender.