World Neurosurg
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Unfamiliarity with the morphometry of the assimilated C1 lateral mass (C1LM) could make screw placement dangerous. In the present study, we defined the morphometric dimensions of the occipitalized C1LM to provide surgeons with valuable information for preoperative planning. ⋯ Although the hypoplastic C1LM brings limitations to screw insertion to some extent, it is still broad enough to accommodate a screw safely in both female and male patients. Considering the irregularity of the C1LM in patients with OA, the preoperative imaging assessment is critical, and C1LM screw placement should be performed individually.
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An academic genealogy describes mentoring relationships in an academic discipline. In this study, we outline an academic genealogy of neurosurgery department chairs in the United States beginning with the founding members of the field. ⋯ The academic genealogy in this study allows for any neurosurgeon trained in the United States to put his or her training into historical context. It also provides a reference for bibliographic research to quantitatively describe the influence of individuals and institutions on the field.
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To discuss lessons learned from an initial lateral lumbar interbody fusion (LLIF) experience with a focus on evolving surgical technique, complication avoidance, and new motor and sensory outcomes after implementation of a modified surgical approach. ⋯ The adoption of an exclusive mini-open muscle-splitting approach with first-look inspection of the lumbosacral plexus nerve elements may improve motor and sensory outcomes in general and the incidence of postoperative groin/thigh sensory dysfunction and psoas-pattern weakness in particular.
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The purpose of this study was to determine reference values for the sagittal plane alignment of the thoracolumbar junction (TLJ) in a young adult Korean population. ⋯ This study provides reference values with a wide physiologic range for the sagittal alignment of the TLJ of the spine in a young adult Korean population.
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MicroRNAs (miRNAs) are a class of small noncoding RNAs that play important roles in tumor development and progression. miR-20a acts as an oncogene in many cancers; however, the underlying role of miR-20a in human glioma remains unknown. ⋯ Collectively, these results suggest a critical role for miR-20a in glioma cell apoptosis, proliferation, and invasion via the direct targeting of CELF2 and indicate its potential application in cancer therapy.