World Neurosurg
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Erythrosine (E127), a synthetic food dye containing iodine and sodium, has often been used inside packaged foods and beverages in Turkey and many other countries. We evaluated the effects of erythrosine on neural tube development in early-stage chicken embryos. ⋯ Erythrosine increased the risk of neural tube defects in early-stage chicken embryos, even at half of the approved dose.
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To assess the dynamic change of the dural sac size in patients with lumbar spinal stenosis (LSS) from supine to standing position and their correlation with clinical symptoms. ⋯ Dural sac size on MRI was reduced significantly from supine to standing position. Standing MRI and the changes of DCSA significantly correlated with claudication distance and VAS score of leg pain in patients with LSS. Therefore, standing MRI provides more radiologic information correlating with clinical symptoms in patients with LSS than supine MRI.
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Meningeal melanocytoma is a rare benign lesion found in the central nervous system. Preoperative diagnosis of meningeal melanocytoma is often a diagnostic challenge, as the clinical and neurologic features are often nonspecific. Various characteristics, including the natural course of this tumor, remain poorly understood. We report a case of a rapidly growing dumbbell-shaped melanocytoma compressing the spinal cord that manifested 2 years after a tumor was identified at the right C2-C3 foramen. ⋯ It is important to include meningeal melanocytoma in the differential diagnosis of dumbbell tumors, as meningeal melanocytomas may show rapid progression.
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An unruptured anterior circulation, nongiant saccular cerebral aneurysm (located at the clinoid segment [C3] of the internal carotid artery [ICA] and growing into the carotid cave) was detected at a medical checkup and diagnosed from subsequent examinations. The aneurysm was observed and followed up with radiologic examinations. An examination performed 12 years after diagnosis revealed the disappearance of the aneurysm. This observation should be kept in mind, that it is possible for an unruptured aneurysm to undergo spontaneous thrombosis without any intervention.
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To conduct an autonomous robot-based neurosurgical procedure in the least time with high accuracy. Further, to analyze and validate the method. ⋯ The robot is successful in conducting hands-off neuroregistration and neuronavigation. The accuracy is considerably higher, and the time taken is lesser relative to the manual procedure.