World Neurosurg
-
Glioma is a common primary intracranial tumor, with high infiltration and aggression. Propofol (Pro) is associated with growth and metastasis in glioma. Meanwhile, circular RNA non-SMC condensin I complex subunit G (circNCAPG; hsa_circ_0007244) has been reported to be upregulated in glioma. This study explored the role and mechanism of circNCAPG in Pro-induced glioma progression. ⋯ Pro could inhibit glioma cell growth and metastasis through the circNCAPG/miR-200a-3p/RAB5A axis, providing a promising therapeutic strategy for glioma treatment.
-
Case Reports
Full-endoscopic resection of a recurrent posterior longitudinal ligament cyst: technical note.
Posterior longitudinal ligament cysts are very rare lesions and do not usually recur. Microscopic resection is commonly performed. The aim of this article was to report a case of recurrent posterior longitudinal ligament cyst that benefited from full-endoscopic resection. ⋯ Endoscopy is a safe and feasible approach for posterior longitudinal ligament cysts, including unusual recurrent cases.
-
Ischemic stroke is the fifth leading cause of death in the United States. Smoking accelerates the onset of stroke by 10 years. The effects of smoking status on percent change in National Institutes of Health Stroke Scale (NIHSS) score, infarct volume, and edema volume were examined following mechanical thrombectomy for large vessel occlusion in patients with acute ischemic stroke. ⋯ These findings are valuable for patient counseling, particularly for women, for smoking cessation.
-
To investigate the role of transforming growth factor β1 (TGF-β1), Smad3, and phospho-Smad3 (p-Smad3) in the invasion of somatotropinomas. ⋯ Low expression of p-Smad3 is correlated with invasion of somatotropinomas.
-
Our aim was to re-evaluate the h-index of neurosurgical units in the United Kingdom and Ireland because it was 5 years since it was last reported. ⋯ The h-index for neurosurgical units is the most reliable bibliometric, which shows the academic standing and correlates well with amount of research grant obtained and size of department. It is particularly useful when calculated for the most recent 10-year and 5-year periods. Neurosurgical units change their rankings over time and, therefore, it is important to update the tables periodically. We propose an online database with open access showing all h-index and bibliometric data for neurosurgical units in the United Kingdom and Ireland. This database could provide a live and dynamic report of the academic standings of those units and could be used for grant applications and reviews.