World Neurosurg
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The bidirectional causal relationship between ischemic stroke(IS) and inflammatory bowel disease(IBD) remains unclear, prompting us to propose a bidirectional Mendelian randomization study to investigate this relationship further. ⋯ IBD and its subtypes were not found to be causally associated with the risk of IS, whereas IS was found to be causally associated with the risk of CD and UC. This suggests that the risks of CD and UC should be closely monitored in patients with IS.
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Neurosurgical care is difficult to access in many scenarios. Aeromedical evacuation of acutely unwell neurosurgical patients from remote, isolated, or poorly equipped locations can be considered. This article aims to provide a framework of logistical factors that deserve special consideration in the preparation of these patients for transfer. ⋯ Although there is little published information, this review provides useful criteria and parameters needed for safe aeromedical evacuation of neurosurgical patients.
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Different from typical primary central nervous system lymphoma (PCNSL), early-stage atypical PCNSL usually presents as patchy signal abnormalities without evident mass effect or significant contrast-enhancement and is prone to confusion with low-grade glioma (LGG). This study aims to develop an MRI-based radiomics model to differentiate early-stage atypical PCNSL from LGG. ⋯ The MRI-based radiomics model can accurately differentiate early-stage atypical PCNSL from LGG with similar radiological manifestations, allowing early-stage atypical PCNSL patients to receive timely and appropriate radiotherapy or chemotherapy while avoiding unnecessary surgical resection.
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The neuroinflammatory response to aneurysmal subarachnoid hemorrhage (SAH) might have a crucial impact on the burden of disease. We aimed to analyze the behavior of interleukin-6 (IL-6) in cerebrospinal fluid (CSF) during SAH and its relation to complications and outcomes. ⋯ Our data confirm the substantial impact of neuroinflammation on SAH. CSF IL-6 values measured during the first week after SAH occurrence present the most valuable outcome predictors.
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To investigate the performances of time-resolved angiography with stochastic trajectories (TWIST-MRA) and dual-source CT angiography (CTA), applied independently and in combination, for preoperative assessment of SVM. ⋯ Both TWIST-MRA and dual-source CTA are reliable for diagnosing SVM and localizing the feeding artery and fistula. While TWIST-MRA remains the primary technique for preoperative diagnosis of SVM, the addition of dual-source CTA can improve diagnostic confidence. CTA may be considered as an alternative to TWIST-MRA for SVMs in the cervical and lumbosacral regions.