Thromb Haemostasis
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Obesity is a major risk factor for cardiovascular disease and its complications. However, not all fat depots share the same characteristics. ⋯ Subsequently the adipose tissue becomes dysfunctional, thus inducing systemic metabolic alterations (through release of cytokines) or specific organ dysfunctions. The purpose of this review is to summarise the current available data on the impact of excess adiposity vs ectopic fat in the development of cardio-metabolic diseases.