The Journal of clinical endocrinology and metabolism
The most recent articles from:
September 2010
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J. Clin. Endocrinol. Metab. · Sep 2010
Meta AnalysisEffects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data.
HIV patients treated with antiretroviral therapy (ART) often develop increased visceral adipose tissue (VAT). ⋯ Treatment with tesamorelin reduces VAT and maintains the reduction for up to 52 wk, preserves abdominal sc adipose tissue, improves body image and lipids, and is overall well tolerated without clinically meaningful changes in glucose parameters.