Swed Dent J
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Randomized Controlled Trial Comparative Study Clinical Trial
Treatment effect on signs and symptoms of temporomandibular disorders--comparison between stabilisation splint and a new type of splint (NTI). A pilot study.
The aim of the investigation was to compare the effect on signs and symptoms of temporomandibular disorders (TMD) of two different interocclusal appliances. Thirty patients with signs and symptoms of TMD received either a stabilisation splint or a new kind of splint based on the concept of nociceptive trigeminal inhibition (NTI). A clinical examination was performed and subjective symptoms were registered before start of treatment and after 3 and 6 months. ⋯ All 14 who had been treated with a stabilisation splint reported some (n = 2) or significant (n = 12) improvement. For all variables registered, the results were in favour for the stabilisation splint. One subject treated with a NTI splint exhibited an impaired occlusion at the 6-month follow-up.
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Randomized Controlled Trial Comparative Study Clinical Trial
Acetylsalicylic acid compared with acetylsalicylic acid plus codeine as postoperative analgesics after removal of impacted mandibular third molars.
In a multicenter, double blind clinical trial a combination of acetylsalicylic acid 500 mg + codeine phosphate 30 mg has been compared with acetylsalicylic acid 500 mg as postoperative analgesics in patients with pain after surgical removal of impacted mandibular third molars. Evaluation of the results from 129 patients showed that the combination of acetylsalicylic acid and codeine provided better pain relief and also the number of tablets used was smaller and the time intervals between repeated doses were longer than with acetylsalicylic acid only. Adverse effects were few and similar for both drugs. It may be concluded that the combination of 500 mg acetylsalicylic acid and 30 mg codeine phosphate provides a useful analgesic for more severe pain conditions in oral surgery.