Circ Cardiovasc Qual
-
Circ Cardiovasc Qual · Jul 2013
Randomized Controlled Trial Multicenter Study Comparative StudyA multicenter, randomized trial of a nurse-led, home-based intervention for optimal secondary cardiac prevention suggests some benefits for men but not for women: the Young at Heart study.
We examined the impact of a prolonged secondary prevention program on recurrent hospitalization in cardiac patients with private health insurance. ⋯ Australian New Zealand Clinical Trials Registry Unique Identifier: 12608000014358. URL: http://www.anzctr.org.au/trial_view.aspx?id=82509.
-
Circ Cardiovasc Qual · Jul 2013
Multicenter StudyRisks and benefits of anticoagulation in atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry.
Patients with atrial fibrillation (AF) at the highest stroke risk derive the largest benefit from oral anticoagulation (OAC). Those with the highest stroke risk have been paradoxically less likely to receive OAC. This study assessed the association between stroke and bleeding risk on rates of OAC. ⋯ In community-based outpatients with AF, use of OAC was high and driven by not only predominantly stroke but also bleeding risk. Stroke risk significantly affects OAC use among those with low bleeding risk, whereas those with high bleeding risk demonstrate consistently lower use of OAC regardless of stroke risk.
-
Circ Cardiovasc Qual · Jul 2013
Hospital strategies associated with 30-day readmission rates for patients with heart failure.
Reducing hospital readmission rates is a national priority; however, evidence about hospital strategies that are associated with lower readmission rates is limited. We sought to identify hospital strategies that were associated with lower readmission rates for patients with heart failure. ⋯ Several strategies were associated with lower hospital RSRRs for patients with heart failure.
-
Circ Cardiovasc Qual · Jul 2013
Review Meta AnalysisComparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials.
Our objective was to estimate the comparative harms of individual statins using both placebo-controlled and active-comparator trials. ⋯ As a class, adverse events associated with statin therapy are not common. Statins are not associated with cancer risk but do result in a higher odds of diabetes mellitus. Among individual statins, simvastatin and pravastatin seem safer and more tolerable than other statins.
-
Circ Cardiovasc Qual · Jul 2013
Randomized Controlled TrialFeasibility and utility of screening for depression and anxiety disorders in patients with cardiovascular disease.
Depression and anxiety in patients with cardiac disease are common and independently associated with morbidity and mortality. We aimed to explore the use of a 3-step approach to identify inpatients with cardiac disease with depression, generalized anxiety disorder (GAD), or panic disorder; understand the predictive value of individual screening items in identifying these disorders; and assess the relative prevalence of these disorders in this cohort. ⋯ Unique Identifier: NCT01201967. URL: http://www.clinicaltrials.gov/ct2/show/NCT01201967.