The Journal of pediatrics
-
The Journal of pediatrics · Feb 2009
Randomized Controlled TrialRandomized trial of milrinone versus placebo for prevention of low systemic blood flow in very preterm infants.
To assess the effectiveness of early prophylactic milrinone versus placebo for prevention of low systemic blood flow in high-risk preterm infants. ⋯ Milrinone did not prevent low systemic blood flow during the first 24 hours in very preterm infants, and no adverse effects were attributable to milrinone. Use of a preventative treatment with rescue model allowed comparison of an inotrope with placebo in this high-risk group of infants.