The Journal of pediatrics
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The Journal of pediatrics · Jul 2014
Review Meta AnalysisHypotonic versus isotonic fluids in hospitalized children: a systematic review and meta-analysis.
To determine whether the use of hypotonic vs isotonic maintenance fluids confers an increased risk of hyponatremia in hospitalized children. ⋯ In hospitalized children in intensive care and postoperative settings, the administration of hypotonic maintenance fluids increases the risk of hyponatremia when compared with administration of isotonic fluids. For patients on general wards, insufficient data are available based on the reviewed studies, and individual risk factors must be assessed.