The Journal of pediatrics
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The Journal of pediatrics · Apr 2015
Randomized Controlled TrialVasopressin versus dopamine for treatment of hypotension in extremely low birth weight infants: a randomized, blinded pilot study.
To evaluate vasopressin vs dopamine as initial therapy in extremely low birth weight (ELBW) infants with hypotension during the first 24 hours of life. ⋯ Vasopressin in ELBW infants as the initial agent for early hypotension appeared safe. This pilot study supports a larger randomized controlled trial of vasopressin vs dopamine therapy in ELBW infants with hypotension.
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The Journal of pediatrics · Apr 2015
Plasma and cerebrospinal fluid herpes simplex virus levels at diagnosis and outcome of neonatal infection.
To evaluate the utility of quantitative herpes simplex virus (HSV) polymerase chain reaction (PCR) levels for prognosis and management of neonatal HSV disease. ⋯ Plasma HSV levels correlate with clinical presentation of neonatal HSV disease and mortality, but not neurologic outcome.
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The Journal of pediatrics · Apr 2015
Review Meta AnalysisDiagnosing clinically significant dehydration in children with acute gastroenteritis using noninvasive methods: a meta-analysis.
To determine the most accurate, noninvasive method of assessing dehydration. ⋯ Overall, the clinical scales evaluated provide some improved diagnostic accuracy. However, test characteristics indicate that their ability to identify children both with and without dehydration is suboptimal. Current evidence does not support the routine use of ultrasound or urinalysis to determine dehydration severity.
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The Journal of pediatrics · Apr 2015
Randomized Controlled Trial Multicenter StudyA randomized clinical trial of therapeutic hypothermia mode during transport for neonatal encephalopathy.
To determine if temperature regulation is improved during neonatal transport using a servo-regulated cooling device when compared with standard practice. ⋯ Cooling using a servo-regulated device provides more predictable temperature management during neonatal transport than does usual care for outborn newborns with neonatal encephalopathy.