The Journal of pediatrics
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The Journal of pediatrics · Sep 2005
Overweight and obesity in deltaF508 homozygous cystic fibrosis.
Overweight (9%) and obesity (1%) in patients with cystic fibrosis homozygous for the deltaF508 mutation (CFdeltaF508) were non-trivial. Children with CFdeltaF508, in contrast to the general population, showed a positive association between body mass index and lung function for all body mass index z-scores.
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The Journal of pediatrics · Aug 2005
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialComparative efficacy and safety of low-dose fluticasone propionate and montelukast in children with persistent asthma.
To evaluate efficacy, safety, health outcomes, and cost-effectiveness of fluticasone propionate (FP) versus montelukast (MON) in 342 children (6 to 12 years of age) with persistent asthma. ⋯ FP was significantly more effective than MON in improving pulmonary function, asthma symptoms, and rescue albuterol use. Both therapies had similar safety profiles. Parent- and physician-reported satisfaction ratings were higher with FP treatment, and asthma-related costs were lower.