The Journal of pediatrics
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The Journal of pediatrics · Oct 2010
Randomized Controlled TrialNebulized 5% or 3% hypertonic or 0.9% saline for treating acute bronchiolitis in infants.
To compare the efficacy and safety of 5%, 3%, and 0.9% saline solution for treating acute bronchiolitis in the prehospital setting. ⋯ Nebulization with 5% hypertonic saline is safe, can be widely generalizable, and may be superior to current treatment for early outpatient treatment of bronchiolitis.
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The Journal of pediatrics · Sep 2010
Randomized Controlled Trial Multicenter StudySelective head cooling with mild systemic hypothermia after neonatal hypoxic-ischemic encephalopathy: a multicenter randomized controlled trial in China.
To investigate the efficacy and safety of selective head cooling with mild systemic hypothermia in hypoxic-ischemic encephalopathy (HIE) in newborn infants. ⋯ Selective head cooling combined with mild systemic hypothermia for 72 hours may significantly decrease the combined outcome of severe disability and death, as well as severe disability.
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The Journal of pediatrics · Jun 2010
Randomized Controlled TrialHeat loss prevention in very preterm infants in delivery rooms: a prospective, randomized, controlled trial of polyethylene caps.
To evaluate in preterm infants whether polyethylene caps prevent heat loss after delivery better than polyethylene occlusive wrapping and conventional drying. ⋯ For very preterm infants, polyethylene caps are comparable with polyethylene occlusive skin wrapping to prevent heat loss after delivery. Both these methods are more effective than conventional treatment.
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The Journal of pediatrics · Feb 2010
Randomized Controlled Trial Comparative StudyPrevention of hyponatremia during maintenance intravenous fluid administration: a prospective randomized study of fluid type versus fluid rate.
To determine the importance of sodium content versus administration rate of intravenous fluids in the development of hyponatremia in postoperative children. ⋯ The risk of hyponatremia was decreased by isotonic saline solution but not fluid restriction.
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The Journal of pediatrics · Dec 2009
Randomized Controlled TrialCan montelukast shorten prednisolone therapy in children with mild to moderate acute asthma? A randomized controlled trial.
To examine whether outpatient post-stabilization therapy with montelukast produces more treatment failures than prednisolone. ⋯ Montelukast does not represent an adequate alternative to corticosteroids after outpatient stabilization in mild to moderate acute asthma. This population should receive oral corticosteroids after discharge.