The Journal of pediatrics
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The Journal of pediatrics · Feb 2016
Randomized Controlled TrialTrimethoprim-Sulfamethoxazole Therapy Reduces Failure and Recurrence in Methicillin-Resistant Staphylococcus aureus Skin Abscesses after Surgical Drainage.
To determine whether a 3-day vs 10-day course of antibiotics after surgical drainage of skin abscesses is associated with different failure and recurrence rates. ⋯ Patients with MRSA skin abscesses are more likely to experience treatment failure and recurrent skin infection if given 3 rather than 10 days of trimethoprim-sulfamethoxazole after surgical drainage.
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The Journal of pediatrics · Jan 2016
Randomized Controlled Trial Multicenter StudyImpact of Continuous Capnography in Ventilated Neonates: A Randomized, Multicenter Study.
To compare the time spent within a predefined safe range of CO2 (30-60 mmHg) during conventional ventilation between infants who were monitored with distal end-tidal CO2 (dETCO2, or capnography) and those who were not. ⋯ Continuous dETCO2 monitoring improved control of CO2 levels within a safe range during conventional ventilation in a neonatal intensive care unit.
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The Journal of pediatrics · Sep 2015
Randomized Controlled Trial Multicenter StudyAutomated versus Manual Oxygen Control with Different Saturation Targets and Modes of Respiratory Support in Preterm Infants.
To determine the efficacy and safety of automated adjustment of the fraction of inspired oxygen (FiO2) in maintaining arterial oxygen saturation (SpO2) within a higher (91%-95%) and a lower (89%-93%) target range in preterm infants. ⋯ A-FiO2 control improved SpO2 targeting across different SpO2 ranges and reduced hypoxemia in preterm infants on noninvasive and invasive respiratory support.
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The Journal of pediatrics · Aug 2015
Randomized Controlled TrialSupreme Laryngeal Mask Airway versus Face Mask during Neonatal Resuscitation: A Randomized Controlled Trial.
To assess the effectiveness of supreme laryngeal mask airway (SLMA) over face mask ventilation for preventing need for endotracheal intubation at birth. ⋯ In newborns with gestational age ≥34 weeks and/or expected birth weight ≥1500 g needing PPV at birth, the SLMA is more effective than face mask to prevent endotracheal intubation. The SLMA is effective in clinical practice after a short-term educational intervention.
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The Journal of pediatrics · Jul 2015
Randomized Controlled Trial Multicenter StudyMask versus Nasal Tube for Stabilization of Preterm Infants at Birth: Respiratory Function Measurements.
To compare the nasal tube with face mask as interfaces for stabilization of very preterm infants at birth by using physiological measurements of leak, obstruction, and expired tidal volumes during positive pressure ventilation (PPV). ⋯ The use of a nasal tube led to large leak, more obstruction, and inadequate tidal volumes compared with face mask.