Bmc Med Res Methodol
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Bmc Med Res Methodol · Apr 2009
Meta AnalysisQuality of reporting internal and external validity data from randomized controlled trials evaluating stents for percutaneous coronary intervention.
Stents are commonly used to treat patients with coronary artery disease. However, the quality of reporting internal and external validity data in published reports of randomised controlled trials (RCTs) of stents has never been assessed.The objective of our study was to evaluate the quality of reporting internal and external validity data in published reports of RCTs assessing the stents for percutaneous coronary interventions. ⋯ The current reporting of results of RCTs testing stents needs to be improved to allow readers to appraise the risk of bias and the applicability of the results.
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Bmc Med Res Methodol · Apr 2009
Does direction of results of abstracts submitted to scientific conferences on drug addiction predict full publication?
Data from scientific literature show that about 63% of abstracts presented at biomedical conferences will be published in full. Some studies have indicated that full publication is associated with the direction of results (publication bias). No study has looked into the occurrence of publication bias in the field of addiction. ⋯ Clinical trials were the minority of abstracts presented at the CPDD; we found evidence of possible publication bias in the field of addiction, with negative or null results having half the likelihood of being published than positive ones.