The American journal of clinical nutrition
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Randomized Controlled Trial
Acute partial sleep deprivation increases food intake in healthy men.
Acute partial sleep deprivation increases plasma concentrations of ghrelin and decreases those of leptin. ⋯ One night of reduced sleep subsequently increased food intake and, to a lesser extent, estimated physical activity-related energy expenditure in healthy men. These experimental results, if confirmed by long-term energy balance measurements, suggest that sleep restriction could be a factor that promotes obesity. This trial was registered at clinicaltrials.gov as NCT00986492.