The American journal of clinical nutrition
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Randomized Controlled Trial Comparative Study
Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men.
Sarcopenia has been attributed to a diminished muscle protein synthetic response to food intake. Differences in digestion and absorption kinetics of dietary protein, its amino acid composition, or both have been suggested to modulate postprandial muscle protein accretion. ⋯ Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men. This effect is attributed to a combination of whey's faster digestion and absorption kinetics and higher leucine content. This trial was registered at clinicaltrials.gov as NCT00557388.