The American journal of clinical nutrition
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Review Meta Analysis
Prenatal folic acid and risk of asthma in children: a systematic review and meta-analysis.
Childhood asthma has become a critical public health problem because of its high morbidity and increasing prevalence. The impact of nutrition and other exposures during pregnancy on long-term health and development of children has been of increasing interest. ⋯ Our findings do not support an association between periconceptional folic acid supplementation and increased risk of asthma in children. However, because of the limited number and types of studies in the literature, additional research is needed.