Zh Nevrol Psikhiatr
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Diagnostic approaches to depression have been changed during last decades. The criteria of a depressive episode have become more formalized but too broad. ⋯ It is making possible to reveal a lot of typical and atypical depressive conditions, and to offer an aid for many people with mental health problems. At the same time, the absence of the strict clinical criteria didn't allow to "translate" modern instrumental findings into scientific understanding of depression and, further on, into practice.
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Zh Nevrol Psikhiatr · Jan 2012
[Complex therapy of idiopathic forms of epilepsy with small doses of valproates and levetiracetam].
A combination of valproates in dose 15-25 mg per day and levetiracetam in dose 20-25 mg per day was used in the treatment of 23 patients with different forms of epilepsy (juvenile myoclonic epilepsy, juvenile absence epilepsy, convulsive idiopathic generalized epilepsy and children absence epilepsy). The use of these drugs was effective in all forms of epilepsy. There were positive changes in the frequency of seizures and epileptic activity in the EEG.
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Zh Nevrol Psikhiatr · Jan 2012
[Experience in using xeomin in the treatment of arm and hand spasticity in the early rehabilitation phase of stroke].
To reduce arm and hand spasticity, 28 patients in the early rehabilitation phase of ischemic hemisphere stroke received injections of the botulinum toxin A preparation xeomin in the content of complex rehabilitation programs. The following muscles: m. biceps brachii, m. flexor digitorum profundus, m. flexor digitorum superficialis, m. flexor carpi ulnaris, m. flexor carpi radialis were injected according to standard scheme. The total dose of drug was 200U in moderate (2-3 scores on the Ashworth scale) and 300U in marked (3-4 scores on the Ashworth scale) spasticity. ⋯ The treatment was most effective in the group of patients with moderate spasticity. The correlation analysis confirmed that the severity of spasticity increased with the disease duration that reduced rehabilitation efficiency. The treatment with xeomin was safe, no serious side-effects were found.
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Zh Nevrol Psikhiatr · Jan 2012
[Valdoxan (agomelatine) in combined therapy of moderate and severe non-psychotic depressions].
According to data received from the study VREMYA, the combined therapy of moderate and severe non-psychotic depressions with Valdoxane and antidepressants of other pharmacological groups is effective and doesn't cause serious adverse events. These findings suggested using the indicated combination of antidepressants in treatment of resistant affective disorders.