Zh Nevrol Psikhiatr
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Zh Nevrol Psikhiatr · Jan 2012
[Idiopathic generalized epilepsy in young women: choise of treatment strategy].
We studied 279 women, aged 18-40 years old, with epilepsy. The study included the evaluation of anamnesis, clinical and neurological examination, routine EEG and/or video-EEG-monitoring, MRI of the brain. The period of observation was 6 months - 8 years. ⋯ Adverse events were found in 22 of 63 (34.9%) patients treated with valproates, 9 of 25 (36%) patients treated with topiramate, 5 of 39 (1.8%) patients treated with carbamazepine, 3 of 7 (42.9%) patients treated with levetiracetam and in 2 of 5 (40%) patients treated with lamotrigine. The aggravation of absences with carbamazepine was diagnosed in 2 cases, myoclonic seizures - in 2 cases. Therapeutic strategies of young women with juvenile forms of IGE were described and analyzed.
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Zh Nevrol Psikhiatr · Jan 2012
[Diagnosis of sympathetically maintained pain in posttraumatic complex regional pain syndrome with laser Doppler flowmetry].
Forty-nine patients with posttraumatic complex regional pain syndrome (CRPS) of the upper extremities were investigated by laser Doppler flowmetry (LDF) with wavelet-analysis of skin blood flow oscillations. Clinical evaluation of sympathetically maintained pain was carried out after the thoracoscopic clipping above and below the Тh3 ganglion of sympathetic chain) in 33 patients and after the perivascular sympathectomy at the level of brachial artery and veins) in 16 patients. The objective diagnosis of sympathetically maintained pain was created with LDF; it was directed specially to discovery of sensory-sympathetic coupling in CRPS. Sensitivity of preoperative LDF − diagnosis was 90.2%, specificity − 87.5%, positive predictive value − 97.3%, negative predictive value − 63.6%, diagnostic effectiveness − 89.8%.