J Otolaryngol Head N
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J Otolaryngol Head N · Feb 2011
Randomized Controlled Trial Comparative StudyDouble-blinded, randomized, controlled trial of medicated versus nonmedicated merocel sponges for functional endoscopic sinus surgery.
This study aimed to compare differences between medicated and nonmedicated Merocel middle meatal spacers (MMSs) on sinonasal mucosal healing (histopathologic and endoscopic difference), patient discomfort, and pain on removal of the MMS following functional endoscopic sinus surgery. ⋯ Although our study failed to show any significant benefit from the addition of medication to the Merocel MMS, further studies with different compounds are recommended to determine whether a medicated MMS could indeed be a superior alternative to the standard MMS.
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J Otolaryngol Head N · Aug 2010
Randomized Controlled Trial Comparative StudyEfficacy of topical levobupivacaine in control of postoperative pain after septoplasty.
To search the efficacy of using Merocele (Medtronic, Minneapolis, MN) soaked with 5 mL of levobupivacaine hydrocloride as a nasal pack in control of postoperative pain after septoplasty. ⋯ Postoperative pain after septoplasty owing to nasal packing is an important problem, and using levobupivacaine-soaked Merocele as a nasal pack after septoplasty is an effective method for the control of this pain. It is a very easy, effective, and quick method and it improves patient comfort after septoplasty.
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J Otolaryngol Head N · Aug 2010
Randomized Controlled Trial Comparative StudyInfluence of nondepolarizing muscle relaxants on intraoperative neuromonitoring during thyroid surgery.
The objective of this study was to find a nondepolarizing muscle relaxant to replace succinylcholine during thyroid surgery with intraoperative neuromonitoring (IONM) because succinylcholine can cause severe adverse effects. ⋯ A single dose (0.5 mg/kg) of rocuronium and atracurium was feasible for IONM during thyroid surgery. This study showed that 44 minutes after administration of these two muscle relaxants is adequate for eliciting an EMG signal from the vagus nerve.
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J Otolaryngol Head N · Feb 2010
Randomized Controlled TrialReducing the flavour of oral lidocaine: randomized controlled trial assessing the efficacy of mint-flavoured mouthwash.
To test the hypothesis that using an alcohol-based, mint-flavoured oral mouthwash prior to applying oral lidocaine spray will result in an improvement in the unpleasant taste of the lidocaine. ⋯ A brief rinse with a mint-flavoured, alcohol-based mouthwash prior to administration of topical lidocaine resulted in a significant improvement in the perceived flavour of topical lidocaine with a minimal reduction in subjective analgesia.
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J Otolaryngol Head N · Oct 2009
Randomized Controlled Trial Comparative StudyComparison of ibuprofen and acetaminophen with codeine following cosmetic facial surgery.
To compare the efficacy and side effects of ibuprofen and acetaminophen with codeine when given postoperatively following cosmetic facial surgery and to assess whether bruising is worse or the incidence of hematoma is greater when ibuprofen is taken postoperatively. ⋯ Ibuprofen 400 mg is as effective as acetaminophen/codeine 600/60 mg for pain relief following cosmetic facial surgery. Ibuprofen is better tolerated, with fewer side effects, than acetaminophen with codeine. Ibuprofen given postoperatively does not result in increased bruising or increased incidence of hematoma.