The Journal of urology
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The Journal of urology · Nov 2000
ReviewNeoadjuvant hormonal ablative therapy before radical prostatectomy: a review. Is it indicated?
Neoadjuvant hormonal ablation therapy has been used to decrease the rate of positive surgical margins in patients treated with radical prostatectomy. We reviewed the available literature to determine whether this therapy is indicated and beneficial. ⋯ Analysis of the available literature revealed no significant improvement in outcome to support the routine administration of neoadjuvant hormonal therapy before prostatectomy.