The Journal of urology
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The Journal of urology · Feb 2004
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialOnce daily, extended release ciprofloxacin for complicated urinary tract infections and acute uncomplicated pyelonephritis.
We assessed the efficacy and safety of 1,000 mg extended release ciprofloxacin orally once daily vs conventional 500 mg ciprofloxacin orally twice daily, each for 7 to 14 days, in patients with a complicated urinary tract infection (cUTI) or acute uncomplicated pyelonephritis (AUP). ⋯ Extended release ciprofloxacin at a dose of 1,000 mg once daily was as safe and effective as conventional treatment with 500 mg ciprofloxacin twice daily, each given orally for 7 to 14 days in adults with cUTI or AUP. It provides a convenient, once daily, empirical treatment option.