The Journal of urology
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The Journal of urology · Mar 2012
Multicenter Studyp16(INK4a) is a marker of good prognosis for primary invasive penile squamous cell carcinoma: a multi-institutional study.
We assessed the prognostic role of p16(INK4a) expression in penile cancer with respect to cancer specific survival. ⋯ Results show that p16(INK4a) seems to be a prognostic parameter for primary invasive penile cancer with excellent interobserver reproducibility. At pathology laboratories without antibodies against p16(INK4a) conventional histological determination of koilocytosis by the pathologist also appears to provide important prognostic information for cancer specific survival.