The Journal of urology
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The Journal of urology · Oct 2004
Randomized Controlled Trial Comparative Study Clinical TrialThe efficacy of LMX versus EMLA for pain relief in boys undergoing office meatotomy.
We determined if a difference in pain management occurred when topical anesthetics LMX (formerly ELA-Max, lidocaine 4%) and EMLA (lidocaine 2.5% and prilocaine 2.5%) were compared in boys undergoing office meatotomy for symptomatic meatal stenosis. ⋯ There was no significant difference between LMX and EMLA when applied 45 minutes before meatotomy. When applied 30 minutes before meatotomy LMX provided significantly superior pain management than EMLA.
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The Journal of urology · Aug 2004
Randomized Controlled Trial Comparative Study Clinical TrialComparison of 3 different methods of anesthesia before transrectal prostate biopsy: a prospective randomized trial.
Periprostatic nerve block (PNB) is the most common anesthesia technique used before prostate biopsy. However, needle punctures for anesthetic infiltration may be painful and cause higher infectious complications. We assessed whether addition of rectal lidocaine gel would improve its efficacy. We also investigated the efficacy and safety of tramadol, a codeine derivative, as a noninvasive method. ⋯ Any form of analgesia/anesthesia was superior to none. The combination of PNB plus gel provided significantly better analgesia compared to PNB alone or tramadol. If this can be duplicated in other trials, the combination may be accepted as the new gold standard of anesthesia for prostate biopsy. The efficacy of tramadol was similar to that of PNB, and was free of complications. Therefore, tramadol may have a role before prostate biopsy, which needs to be explored.
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The Journal of urology · Jul 2004
Randomized Controlled Trial Clinical TrialLaboratory based training in urological microsurgery with bench model simulators: a randomized controlled trial evaluating the durability of technical skill.
We evaluated the durability of laboratory based technical skills training in urological microsurgery using bench model simulators. ⋯ Laboratory based technical skills training with bench models can lead to a significant retention of technical skill by novice surgeons. Measured performance improvements appear to be durable with time. However, the opportunity for repeat hands-on practice appears to maximize the retention of technical skill.
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The Journal of urology · Apr 2004
Randomized Controlled Trial Multicenter Study Clinical TrialCost-effectiveness of zoledronic acid for the prevention of skeletal complications in patients with prostate cancer.
We estimated the cost-effectiveness of zoledronic acid vs placebo for decreasing skeletal complications in men with prostate cancer. ⋯ The nominal base case estimate of the cost per quality adjusted life-year for zoledronic acid in the prevention of skeletal complications of prostate cancer is consistent with that of bisphosphonates in breast cancer. However, the cost-effectiveness ratios for bisphosphonates are higher than commonly cited thresholds for conferring cost-effectiveness.
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The Journal of urology · Apr 2004
Randomized Controlled Trial Multicenter Study Clinical TrialTreatment of chronic prostatitis/chronic pelvic pain syndrome with tamsulosin: a randomized double blind trial.
We compared the efficacy of tamsulosin with placebo for the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). ⋯ Tamsulosin was superior to placebo in providing symptomatic relief in men with CP/CPPS, particularly in those with more severe symptoms.