Orvosi hetilap
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Review Meta Analysis Comparative Study
[Antimicrobial therapy of Clostridium difficile infection. Systematic review and meta-analysis of the scientific evidence].
Clostridium difficile is the leading cause of antibiotic associated infectious nosocomial diarrhoea. Limited number of new pharmaceutical products have been developed and registered in the past decades for the treatment of Clostridium difficile infection. The available scientific evidence is limited and hardly comparable. ⋯ Each antibiotic similarly improved clinical cure. Fidaxomicin was the most effective therapeutic alternative in lowering the rate of recurrent Clostridium difficile infections.