Ann Endocrinol Paris
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Ann Endocrinol Paris
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Ann Endocrinol Paris · Sep 1999
Multicenter Study Clinical Trial Controlled Clinical Trial[The effectiveness of oral cyproterone acetate in combination with ethinylestradiol in acne tarda of the facial type].
Cyproterone acetate is a potent antiandrogen with strong progestational activity. In combination with ethinyloestradiol, it has been shown to be of clinical benefit to women displaying signs of androgenization, such as acne, seborrhoea and hirsutism. In addition, this combined oestrogen/progestogen preparation provides effective contraceptive protection. ⋯ EE/CPA is an effective treatment for acne of all grades and all types of lesion. The preparation is well tolerated and would appear to be an appropriate treatment for women with these symptoms of androgenization.