Pediatrics
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Nebulized budesonide is as effective as nebulized adrenaline in moderately severe croup.
Nebulized budesonide and nebulized adrenaline have been shown to be effective in the treatment of moderately severe croup. However, there has been no direct comparison of these therapies. We undertook a multicenter, randomized, double-blind, parallel group study in 66 hospitalized children with viral or spasmodic croup. ⋯ This study does not show any difference in efficacy and safety between nebulized budesonide and nebulized adrenaline in the treatment of acute upper airway obstruction in patients with moderately severe croup.