Pediatrics
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Randomized Controlled Trial Comparative Study Clinical Trial
A controlled trial of dexamethasone to prevent bronchopulmonary dysplasia in surfactant-treated infants.
Surfactant therapy now has a well-established role in the treatment of neonates with respiratory distress syndrome but has failed to reduce the incidence of bronchopulmonary dysplasia (BPD). We conducted a double-blind, placebo-controlled trial to test the hypothesis that dexamethasone therapy given during the first 12 days of life to very low birth weight infants would be synergistic to surfactant in preventing BPD. ⋯ We found an additive effect between dexamethasone and surfactant in improving pulmonary status and reducing the incidence of BPD. Compared with the placebo, dexamethasone therapy was more effective in reducing the incidence of BPD in surfactant-pretreated very low birth weight infants.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Rapid placement of transpyloric feeding tubes: a comparison of pH-assisted and standard insertion techniques in children.
To compare transpyloric feeding tube placement using a pH-assisted placement technique versus a standard placement technique in pediatric patients requiring enteral nutrition. ⋯ Our findings indicate that bedside transpyloric placement of pH-assisted feeding tubes can be accomplished rapidly and with a high success rate. This method is associated with decreased radiation exposure and economic savings when compared with a standard placement technique.