Pediatrics
-
Randomized Controlled Trial Comparative Study
Room-air versus oxygen administration for resuscitation of preterm infants: the ROAR study.
We conducted a blinded, prospective, randomized control trial to determine which oxygen-titration strategy was most effective at achieving and maintaining oxygen saturations of 85% to 92% during delivery-room resuscitation. ⋯ Titrating from an initial oxygen concentration of 100% was more effective than giving a static concentration of 100% oxygen in maintaining preterm infants in a target oxygen saturation range. Initiating resuscitation with 21% oxygen resulted in a high treatment-failure rate.
-
Randomized Controlled Trial Multicenter Study Comparative Study
Evidence for catch-up in cognition and receptive vocabulary among adolescents born very preterm.
Very preterm adolescents display persistent deficits in neuropsychological functions. ⋯ Significant catch-up in receptive vocabulary is observed by the age of 16 years among very preterm children compared to term peers. The absence of neurosensory impairment and residing in a favorable socioeconomic milieu are associated with the most optimal developmental trajectories.