Jpen Parenter Enter
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Parenteral nutrition (PN) is a high-alert medication that contains dozens of active pharmaceutical ingredients. This complex prescription drug preparation is used in a wide variety of clinical settings for patients across the age spectrum. Despite the existence of a number of guidance documents, the drug-use process for PN suffers from lack of standardization for order prescription, order verification and review, PN compounding, labeling, and dispensing. As a result, PN-associated medication errors would not be unexpected but are documented infrequently.
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Jpen Parenter Enter · Mar 2012
Compounding USP <797>: inspection, regulation, and oversight of sterile compounding pharmacies.
Using USP Chapter <797> Pharmaceutical Compounding-Sterile Preparations (CSP) is now considered the standard for sterile compounding practice and safety in the United States. This is particularly important in compounding the complex formulation of parenteral nutrition.
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Jpen Parenter Enter · Mar 2012
Comparative StudyParenteral nutrition prescribing processes using computerized prescriber order entry: opportunities to improve safety.
The prescribing and processing of parenteral nutrition (PN) orders for pediatric patients may involve multiple steps, be time-consuming, and have opportunity for error if safety measures are not in place. The process can vary from institution to institution. The authors conducted a comparison of their system for the prescribing and processing of PN orders with the American Society for Parenteral and Enteral Nutrition's (A. ⋯ There was a 5% overall pharmacist intervention rate on PNs, similar to the 6%-8% rate seen with other medications. Approximately 6% of these PN interventions had an outcome associated with preventing an adverse drug reaction, toxicity, or medication error. Implementation of additional safety measures and standardization may have a positive impact on the complicated process of prescribing and processing PN orders at the authors' institution.
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Parenteral nutrition (PN) is a complex prescription consisting of many components such as dextrose, amino acids, electrolytes, vitamins, trace elements, and/or intravenous fat emulsions. The ordering process is inconsistent and has led to PN errors. PN prescriptions require knowledge, education for prescribers, and standardized processes.
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Safe practices for sterile compounding are essential to preventing errors, particularly with parenteral nutrition (PN). This article reports several areas of errors in PN processes and provides recommendations for error prevention.