Pediatr Crit Care Me
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Pediatr Crit Care Me · Jul 2013
Multicenter StudyUnscheduled readmissions to the PICU: epidemiology, risk factors, and variation among centers.
To determine the rate of, and potential risk factors for, unscheduled PICU readmission and assess for variability among PICUs within the United States. ⋯ The rate of unscheduled PICU readmission was low but associated with worse outcomes. Patient and admission/discharge characteristics associated with increased risk of readmissions could be used to target high-risk populations or modifiable factors to improve outcome. Variation of risk among centers suggests room for improvement.
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Pediatr Crit Care Me · Jul 2013
Clinical TrialSildenafil exposure and hemodynamic effect after stage II single-ventricle surgery.
To determine sildenafil exposure and hemodynamic effect in children after stage II single-ventricle surgery. ⋯ Sildenafil demonstrated nonlinear exposure with high interindividual variability but was well tolerated and effectively lowered pulmonary vascular resistance index in all subjects. Sildenafil did not acutely improve myocardial performance or increase cardiac index.