Pediatr Crit Care Me
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Pediatr Crit Care Me · Sep 2014
ReviewUnderstanding the Global Epidemiology of Pediatric Critical Illness: The Power, Pitfalls, and Practicalities of Point Prevalence Studies.
The point prevalence methodology is a valuable epidemiological study design that can optimize patient enrollment, prospectively gather individual-level data, and measure practice variability across a large number of geographic regions and healthcare settings. The objective of this article is to review the design, implementation, and analysis of recent point prevalence studies investigating the global epidemiology of pediatric critical illness. ⋯ Point prevalence studies in pediatric critical care can efficiently provide valuable insight on the global epidemiology of disease and practice patterns for critically ill children.
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Pediatr Crit Care Me · Sep 2014
ReviewIntensive Care Treatment of Uncontrolled Status Epilepticus in Children: Systematic Literature Search of Midazolam and Anesthetic Therapies.
A systematic literature search and review of the best evidence for intensive care treatment of refractory status epilepticus in children using continuous infusion of midazolam or anesthetic agents. ⋯ The data on intensive care treatment of pediatric refractory status epilepticus are of poor quality, yet they show a hierarchy in strategies: early midazolam, then barbiturates, and then trial of other anesthetic strategies. In addition, using a solely clinical endpoint for seizure control may be missing significant seizure burden in pediatric refractory status epilepticus.