British medical bulletin
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British medical bulletin · Apr 2023
Return to sport or work following surgical management of scapholunate ligament injury: a systematic review.
This systematic review aims to compare the rate and time to return to sport or work following surgical interventions for isolated scapholunate ligament (SLL) injury. ⋯ Prospective, randomized, primary studies are needed to establish optimal treatment for acute isolated SLL injuries.
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British medical bulletin · Apr 2023
Meta AnalysisKnee osteoarthritis, joint laxity and PROMs following conservative management versus surgical reconstruction for ACL rupture: a meta-analysis.
Patients whose rupture of the anterior cruciate ligament (ACL) can be managed conservatively or undergo reconstruction surgery. ⋯ ACL reconstruction provides significant improvement in joint laxity compared to conservative management, but is associated with a significantly greater rate of knee osteoarthritis, despite similar results at PROM assessment.
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British medical bulletin · Apr 2023
Meta AnalysisDoes femoroacetabular impingement syndrome affect range of motion? A systematic review with meta-analysis.
It is unclear whether femoroacetabular impingement syndrome (FAIS) affect hip range of motion (ROM). ⋯ Further studies are needed to resolve the uncertainty of evidence about ROM restrictions in asymptomatic FAIm compared to healthy controls.
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British medical bulletin · Apr 2023
ReviewMethods of assessing value for money of UK-based early childhood public health interventions: a systematic literature review.
Economic evaluation has an important role to play in the demonstration of value for money of early childhood public health interventions; however, concerns have been raised regarding their consistent application and relevance to commissioners. This systematic review of the literature therefore aims to collate the breadth of the existing economic evaluation evidence of these interventions and to identify the approaches adopted in the assessment of value. ⋯ Future resource allocations decisions regarding early childhood public health interventions may benefit from consistency in the evaluative frameworks and health outcomes captured, as well as consistency in approaches to incorporating non-health costs and outcomes, incorporating equity concerns and the use of appropriate time horizons.
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Micro RNAs (miRNAs) are short non-coding RNAs that act primarily in posttranscriptional gene silencing, and are attracting increasing interest in musculoskeletal conditions. ⋯ Intra-articular injection of microRNA-210 in vivo may represent a potential innovative methodology for the management of meniscal injuries. Characterization of the miRNAs expression in the synovial fluid could lead to the development of better early diagnosis and management strategies for meniscal tears.