Crit Care Resusc
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To determine whether hyperglycaemia is associated with prolongation of the corrected QT (QTc) interval on the electrocardiogram (ECG) in critically ill patients. ⋯ There was a moderate, significant correlation between QTc and BGL. Patients with a QTc > 0.44 s had higher BGL, APACHE II score and mortality. BGL was an independent predictor of QTc duration, but neither BGL nor QTc were independent predictors of mortality in this study.
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To determine whether the introduction of a weekly multidisciplinary team meeting (MDTM) to a general intensive care unit improved selected clinical indicators of patient outcome, and staff satisfaction with patient care. ⋯ The introduction of a weekly MDTM to a general ICU did not improve selected clinical indicators of patient outcome or staff satisfaction with patient care.
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To investigate the presence and determinants of femoral-radial gradients in mean arterial pressure (MAP) in a critically ill population. ⋯ A systematic difference in MAP measured at the radial and femoral sites was demonstrated. In some critically ill patients, the femoral artery may be the preferred site for systemic arterial pressure monitoring.
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Randomized Controlled Trial Multicenter Study
The RENAL (Randomised Evaluation of Normal vs. Augmented Level of Replacement Therapy) study: statistical analysis plan.
The Randomised Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study is the largest interventional trial ever conducted in patients with acute renal failure. ⋯ We have developed a pre-determined statistical analysis plan for the RENAL trial. This plan will be adhered to in order to avoid introducing any analysis bias associated with prior knowledge of study findings.
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Randomized Controlled Trial Multicenter Study
The NICE-SUGAR (Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation) Study: statistical analysis plan.
The Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE-SUGAR) Study is the largest study to date of glycaemic control in critically ill patients. ⋯ We have developed a pre-determined statistical analysis plan for the NICE-SUGAR Study. This plan will be followed to avoid analysis bias arising from prior knowledge of the study findings.